Northwest Wyoming
With Grand Teton National Park, and Yellowstone National Park both in the upper Northwest corner of Wyoming, the area has a lot going for it.
Red Desert
The Red Desert, in south/central Wyoming, is touted as being one of the largest unfenced areas in the lower 48. Visiting the Red Desert is like stepping back in time. Huge views unspoiled by building and structures, wild horses, and very few other visitors.